Overview
In this role you will join a multidisciplinary programme on computational proteomics, pursuing de novo sequencing via two-dimensional partial covariance mass spectrometry. You will design and implement advanced computational algorithms and engage in mass spectral data acquisition in an analytical lab. You will collaborate with Imperial College and US project partners to optimize de novo sequencing methods and contribute to cross-lab data campaigns. This is a chance to help establish a new physical paradigm for biomolecular sequencing, with impact across science and technology. You will be part of a world-leading effort aligned with the mission of advancing scientific knowledge and humanity.”
Pay / Benefits
- sector-leading salary and remuneration package
- 41 days’ leave per year
- generous pension schemes
- career support for researchers
- opportunities for promotion and progression
- diverse, inclusive, and collaborative culture
Responsibilities
- Design and implement advanced computational algorithms for de novo peptide sequencing from mass spectral data
- Contribute to mass spectrometry data acquisition in an analytical lab
- Collaborate with Imperial College and US partners to develop and optimize sequencing algorithms
- Participate in data acquisition campaigns across partner laboratories
- Engage in publications, conference presentations, and grant applications
Key requirements
- PhD in Physics or closely related quantitative discipline
- outstanding research record
- strong computational and analytical skills
- experience with novel algorithms, data analysis, or machine learning
- willingness to work at the interface of physics, computation, and biomolecular science
- background in computational physics, ML, signal processing, inverse problems, or applied mathematics (proteomics/mass spectrometry experience not required)
- intellectually ambitious
- self-motivated
- collaborative
- novel algorithm development
- advanced data-analysis methodologies
- scientific software
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