Senior Research Associate, Bioanalytical & Molecular Assays

Overview

In this role you will advance clinical bioanalytical methods to support Moderna’s mRNA programs in a fast-paced, collaborative environment. You’ll develop and transfer assays that meet GCLP standards to generate robust PK/PD data for clinical programs. You will work at the intersection of basic science and clinical development, using cutting-edge molecular biology tools to enable timely program milestones. This position combines hands-on analytics with cross-functional collaboration to drive impactful translational work.

Pay / Benefits

• Best-in-class healthcare
• Fertility, adoption, and surrogacy support
• Generous paid time off and sabbatical options
• Global recharge days and discretionary year-end shutdown
• Savings and investments for the future
• Location-specific perks

Responsibilities

• Perform bioanalytical assays using techniques such as gel electrophoresis, ddPCR, qPCR, RT-qPCR to quantify RNA in biological matrices
• Support integration of basic science and bioanalytical activities within a GCLP-compliant clinical environment
• Lead phase-appropriate assay development, qualification, and validation for PK/PD analyses
• Isolate genomic DNA and RNA and generate high-quality analytical data
• Ensure assays are developed and validated within timelines to support program milestones
• Establish fit-for-purpose bioanalytical methods meeting scientific, regulatory, and GCLP requirements
• Review raw data, validation reports, and study reports for data integrity and compliance
• Collaborate with internal and external labs to meet quality and regulatory expectations
• Support equipment procurement, qualification, maintenance, and lifecycle management
• Prepare and improve SOPs and supporting documentation
• Identify and manage critical reagents for long-term program support
• Collaborate with Clinical Operations, Sample Management, and cross-functional teams on sample journeys and lab manuals
• Maintain detailed electronic lab notebooks and documentation practices
• Contribute to continuous improvement for efficiency, data quality, and compliance
• Leverage digital tools and Generative AI-enabled workflows to enhance processes and data interpretation
• Adapt to a dynamic, fast-paced environment with scientific curiosity and team focus

Key requirements

• M.S. with 5+ years or B.S. with 8+ years in Molecular Biology or related field with GCLP/GLP experience in clinical molecular assays
• Hands-on experience with gel electrophoresis, capillary electrophoresis, and qPCR; experience with NGS and genomics is a plus
• Strong ability to communicate objectives, data analysis, and findings to teams and stakeholders
• Knowledge of GCLP requirements and regulatory expectations for analytical science
• Desire to contribute to a high-growth, transformational company that values boldness, curiosity, and collaboration

• strong communication
• collaborative mindset
• scientific curiosity
• gel electrophoresis
• capillary electrophoresis
• qPCR

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