Research Scientist, Lentiviral Vector Purification and Analytics

Overview

Join the LVV Team at Novartis’ Biologics Research Center in Cambridge as a Research Scientist I/II. You will focus on lentiviral vector purification and analytics to support next-generation CAR-T programs. You will work hands-on across purification, analytics, and technology transfer, collaborating with cross-functional teams to advance cell and gene therapy research. This role offers direct impact on research materials and scalable vector processes in a mission-driven environment. You will contribute to innovative science in a collaborative, fast-paced setting.

Pay / Benefits

• health benefits
• life and disability insurance
• 401(k) with company contribution and match
• performance-based incentive
• annual equity awards eligibility
• generous paid time off

Responsibilities

• Execute lentiviral vector purification activities including clarification, chromatography, and tangential flow filtration (TFF)
• Run and evaluate analytical methods (molecular- and cell-based) to assess vector quality
• Draft and review protocols, technical reports, and technology transfer documents
• Create and update SOPs and instrument procedures
• Plan and prioritize work to meet goals while managing multiple projects
• Support experimental design, data analysis, and troubleshooting
• Identify root causes, implement corrective actions, and verify results
• Present scientific data and engage in cross-team discussions
• Document procedures and processes thoroughly
• Collaborate across teams and train team members as needed

Key requirements

• BS or MS in bioengineering, virology, or related field with lab experience
• 1–3 years of experience in protein and/or viral vector purification
• Hands-on experience with chromatography and filtration, including TFF and depth filtration
• Strong coordination, communication, collaboration, learning agility, and self-motivation
• Proficiency with Word, Excel, PowerPoint, and GraphPad Prism
• Excellent oral, written, and interpersonal communication skills

• collaboration
• learning agility
• self-motivation
• chromatography
• filtration
• TFF

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