Senior Supervisor, Manufacturing (Technical)

Overview

In this role, you will lead upstream activities across fermentation, downstream, and chromatography within a cutting-edge biopharmaceutical facility. You’ll manage cross-functional teams and support new product transfers from R&D to manufacturing, driving continuous improvement and robust process control. You’ll tackle deviations, equipment issues, and scale-up challenges to enable reliable production and scalable product development. This position offers influence on process development and operational excellence in a fast-paced, regulated environment.

Pay / Benefits

• Competitive salary and benefits package
• Support for continual professional development
• Operational excellence initiatives
• Exposure to cutting-edge biopharmaceutical facility
• Chance to influence process development at a senior level

Responsibilities

• Lead the technical team across fermentation, downstream, and chromatography to ensure efficient production and process optimisation
• Investigate deviations and equipment failures, implementing corrective actions to improve performance
• Drive process scale-up, characterisation, and optimisation for new product transfers from R&D
• Monitor operational performance and pursue continuous improvement using Lean, Kaizen, Six Sigma, or Operational Excellence methods
• Support routine manufacturing, oversee validation activities, and ensure compliance with quality and regulatory standards

Key requirements

• Degree or higher in a relevant scientific discipline (Biotechnology, Bioengineering, or similar)
• Experience in large-scale biopharmaceutical manufacturing with knowledge of upstream and downstream techniques
• Extensive experience in cGMP-regulated environments and ISO frameworks (ISO9001/45001/14001)
• Strong leadership, mentoring, and cross-functional team management skills
• Proactive approach to process improvements and high accountability

• Leadership and mentoring
• Effective communication
• Problem-solving
• Upstream and downstream bioprocess techniques
• Process scale-up and optimisation
• Deviations investigation and CAPA

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