Senior Director, Health Economics & Outcomes Research (HEOR)

Overview

In this role you will lead asset-specific payer evidence strategies to strengthen BioMarin’s access and value proposition across therapeutic areas. You will shape patient-relevant outcomes requirements within clinical programs and align them with Regulatory, HTA, and access needs. You will partner with cross-functional teams and external stakeholders to design, execute, and communicate outcomes research that differentiates BioMarin assets in the market. This position offers a chance to influence early access decisions and publish impactful research, contributing to patient access for rare diseases.

Responsibilities

• Lead development, execution and communication of payer evidence strategies aligned with brand priorities for early-stage assets
• Collaborate with Value & Access, Commercial, Medical Affairs, Clinical Development, Regulatory Affairs and Patient Advocacy organizations
• Drive understanding of payer and HTA requirements related to patient-relevant outcomes and health utility measurement
• Oversee asset-specific patient-relevant outcomes strategies informed by disease models
• Lead patient-relevant endpoint planning and trial implementation oversight
• Lead early Joint Clinical Assessment strategy development across markets
• Identify payer evidence gaps and inform integrated evidence planning for pipeline assets
• Manage external partnerships for PRO development, health state valuation, and patient preference research
• Lead scientific interactions with HTA agencies (EU HTA JSC, NICE, CADTH) including briefing materials and evidence packages
• Support regulatory and patient advocacy interactions and communicate value through integrated evidence plans
• Shape exploration and interpretation of trial outcomes data to strengthen HTA and payer value propositions
• Develop strategic scientific communications and publish research in peer-reviewed journals
• Assess BD opportunities against payer/HTA requirements to identify risks and gaps
• In partnership with IET, analyze patient-relevant outcomes data to generate insights for stakeholders

Key requirements

• 12+ years in pharma with 7+ years in HEOR or related roles
• 5+ years direct experience with patient-relevant outcomes research
• Advanced degree in health economics, outcomes research, epidemiology, public health, health services research, pharmacy or related field
• Deep understanding of market access, value and global HTA frameworks
• Proven experience developing and executing patient-relevant outcomes strategies
• Experience in evaluation, development, and validation of PRO measures for regulatory, payer, and HTA decision making
• Experience supporting HTA submissions, value dossiers, and patient-relevant briefing books
• Proven ability to influence across senior cross-functional stakeholders
• Ability to manage multiple complex initiatives in a fast-paced environment
• Leadership experience and external visibility in the PRO field
• Experience engaging with HTA agencies, payers, health economists, experts, and patient organizations
• Rare disease experience preferred
• People leadership experience preferred

• influencing and negotiating with senior stakeholders
• cross-functional collaboration
• strategic thinking and prioritization
• HEOR strategy
• PRO development and validation
• HTA submissions and value dossiers

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