Research Scientist, Synthetic Technologies

Overview

As a Research Scientist II in the Synthesis Technologies Team of Global Discovery Chemistry at NIBR (Cambridge), you drive the synthesis and purification of pharmaceutically relevant molecules from mg to multi-gram scale. You will apply innovative methods, troubleshoot routes, and collaborate across global teams to advance small-molecule drug discovery. You contribute to safe, efficient methods and structural elucidation within a fast-paced research environment. This role offers the opportunity to influence project outcomes and grow within a mission to discover transformative medicines.

Pay / Benefits

• salary range $81,200 – $150,800
• performance-based cash incentive
• eligibility for annual equity awards
• comprehensive benefits package (health, life, disability)
• 401(k) with company contribution and match
• generous time off package

Responsibilities

• Conduct task-oriented synthesis and purification from milligram to multi-gram scale
• Anticipate synthetic pitfalls and optimize routes/conditions
• Explore and deploy cutting-edge synthetic methods for building blocks and drug substances
• Collaborate with internal and external chemistry teams
• Perform structural and stereochemical elucidation
• Adhere to laboratory safety policies

Key requirements

• BS or MS in synthetic organic chemistry with 2–5 years of postgraduate experience
• Strong working knowledge of synthetic organic methodology and multi-step preparation of drug substances
• Excellent observational, organizational, data management, and documentation skills
• Desire for green and sustainable synthesis methods (preferred)
• Outstanding communication skills for cross-functional collaboration with medicinal chemistry teams

• collaboration
• communication
• problem-solving
• synthetic organic chemistry
• multi-step synthesis
• purification

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