Translational Medicine Director/Associate*- Cardiovascular & Metabolic

Company: Novartis
Apply for the Translational Medicine Director/Associate*- Cardiovascular & Metabolic
Location: Cambridge
Job Description:

Overview

In this role you drive PoC-focused translational medicine within Cardiovascular Metabolism, leading global cross-functional teams to design and execute early clinical research. You shape development pathways and biomarker strategies, bridging discovery and patient-ready therapies. You collaborate with biology, chemistry, and regulatory partners to advance PoC programs and, if successful, contribute to full development through registration. The role blends strategic leadership with hands-on medical monitoring and cross-team communication, in a mission to bring meaningful CVM therapies to patients.

Pay / Benefits

  • performance-based cash incentive
  • eligibility for annual equity awards
  • comprehensive benefits package (health, life, disability)
  • 401(k) with company contribution and match
  • generous time off (vacation, personal days, holidays)

Responsibilities

  • Lead global project teams through PoC to implement PoC strategy from NTRC to registration
  • Own clinical portions of the Integrated Development Plan (IDP) through PoC
  • Act as medical monitor for one or more clinical studies
  • Communicate clinical matters to project teams and decision boards
  • Convene internal and external leaders to discuss PoC approaches
  • Evaluate clinical centers and engage collaborating investigators
  • Oversee publication and external presentation of PoC results
  • Be accountable for compound-related biomarker strategies; collaborate with biomarker experts
  • Develop and implement preclinical strategies to support program objectives and assess clinical implications
  • Present to Health Authorities as TM Expert

Key requirements

  • MD required with subspecialty training preferred in cardiovascular disease or endocrinology/metabolic disease
  • 1–2 years’ experience in pharma/biotech/CRO/academic medical center; 5+ years for Director level
  • Recognized for medical and scientific expertise with strong publication record
  • Excellent written and oral communication/presentation skills
  • Ability to work independently on study planning and execution; capable of leading collaborations in a matrix organization
  • Leadership of multidisciplinary teams in a matrix organization
  • Innovative mindset with openness to new clinical discovery opportunities and PoC approaches
  • Fluent in English
  • Additional consideration for advanced data science/genomics/AI applied to clinical research or digital/wearable health science
  • cross-functional collaboration
  • communication and presentation
  • leadership and people management
  • Clinical Trials
  • Cross-Functional Teamwork
  • Data Analysis

Posted: September 14th, 2026