Clinical Safety Manager – Pharmacovigilance / Drug Safety

Overview

In this role you will oversee pharmacovigilance activities for multiple programs within Medpace UK, supporting high-quality safety outcomes for clients. You will work with cross-functional teams to review study documents and safety components, and you’ll contribute to safety planning, audits, and scope/cost estimation efforts. You’ll manage safety programs and mentor junior staff while maintaining regulatory compliance across global requirements. This is an opportunity to shape safety processes in a fast-growing European footprint and advance your leadership in pharmacovigilance.

Pay / Benefits

• Flexible work environment
• Competitive compensation and benefits package
• Competitive PTO packages
• Structured career paths with opportunities for professional growth
• Company-sponsored employee appreciation events
• Employee health and wellness initiatives

Responsibilities

• Manage Clinical Safety activities for multiple programs
• Maintain strong client and internal stakeholder relationships with expert safety input
• Oversee clinical safety case management and aggregate reporting to meet client needs
• Provide safety reviews of protocols, study reports, and marketing components
• Create safety management plans tailored to client requirements
• Participate in business development activities including sponsor presentations, audits, and scope/cost estimation
• Draft departmental SOPs and Work Instructions

Key requirements

• Bachelor’s degree or equivalent with clinical safety experience
• Experience managing clinical safety activities for multiple programs
• Experience writing SOPs and Work Instructions
• Experience in PSMF generation and maintenance
• Experience in CCDS/RMP/SmPC writing and maintenance
• Comprehensive knowledge of global clinical safety regulatory requirements
• Excellent verbal and written communication
• Strong leadership, mentoring, and teamwork skills
• Ability to work independently

• leadership
• mentoring
• teamwork
• pharmacovigilance
• safety review of clinical study documents
• PSMF generation and maintenance

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