Associate Director, Health Economics & Outcomes Research (HEOR)

Overview

In this role you will lead payer evidence strategies and patient-relevant outcomes research to strengthen access for BioMarin assets. You will shape outcome requirements across clinical programs and align with Regulatory, HTA, and access needs. You will collaborate with cross-functional teams and external stakeholders to design and execute evidence projects. This position offers the opportunity to impact market access strategy for rare disease therapies at a global scale. You will work within BioMarin’s Global HEOR team to drive differentiated value propositions.

Responsibilities

• Lead development, execution, and communication of payer evidence strategies aligned with brand and access priorities for early-stage assets
• Collaborate with Value & Access, Commercial, Medical Affairs, Clinical Development, Regulatory Affairs, and Patient Advocacy
• Contribute to understanding payer and HTA requirements related to patient-relevant outcomes and health utility measurement
• Assess and plan patient-relevant outcomes requirements for HTA and access to differentiate value
• Incorporate payer evidence requirements into clinical development plans to enable patient access
• Develop cross-functional, asset-specific patient-relevant outcomes strategies informed by disease models
• Support patient-relevant endpoint planning and implementation in clinical trials
• Lead early Joint Clinical Assessment (JCA) strategy development and assess access implications across markets
• Identify payer evidence gaps and guide future integrated evidence planning for early-stage assets
• Manage external partnerships for PRO development/validation, health state valuation, and patient preference research
• Support scientific interactions with HTA agencies and regulators, including briefing materials and evidence packages
• Lead analysis of trial data to generate insights for HTA, payers, and stakeholders
• Shape scientific communication plans and support publication of research
• Assess BD opportunities against payer/HTA requirements to identify risks and gaps

Key requirements

• 7+ years pharma industry experience with 4+ years in HEOR and 2+ years in patient-relevant outcomes research
• Advanced degree in health economics, outcomes research, epidemiology, public health, health services research, pharmacy, or related field
• Strong understanding of market access, value, and global HTA frameworks
• Experience developing and executing patient-relevant outcomes strategies for payer and HTA requirements
• Experience contributing to PRO measure evaluation, development, and validation
• Experience supporting HTA submissions, value dossiers, and patient-relevant briefing books
• Ability to align cross-functional stakeholders across multiple departments
• Capability to manage multiple initiatives in a dynamic environment
• Emerging expertise in PRO field with a professional network
• Experience engaging with external stakeholders (HTA agencies, payers, health economists, clinicians, patient groups)
• Rare disease experience preferred

• collaboration
• stakeholder alignment
• effective prioritization
• patient-relevant outcomes (PRO) development and validation
• health state valuation studies (time trade-off, standard gamble)
• PRO endpoints planning and interpretation

…