Medical Director Clinical Development- Respiratory

Overview

Experienced Medical Director leads clinical development for Respiratory assets within RIIRU. You will shape translational and clinical plans, support target validation and regulatory documents, and drive end-to-end development strategies with cross-functional teams. The role blends scientific leadership with regulatory and safety governance to deliver differentiated medicines. You will influence programs from early discovery through to clinic, aligning with GSK’s patient-centric mission. This position offers hybrid work and an opportunity to impact patient outcomes at scale.

Pay / Benefits

• annual bonus
• long-term incentive program (share-based)
• healthcare and other insurance benefits
• retirement benefits
• paid holidays and vacation
• paid caregiver/parental and medical leave

Responsibilities

• Align translational and clinical plans with project strategies to ensure quality CDP design and execution
• Lead medical governance and safety oversight across studies
• Develop regulatory documentation sections and briefing materials for regulatory interactions
• Define clinical pillars of translational tables and oversee end-to-end clinical development strategy for early programs
• Establish strong cross-functional relationships with Biology, Translational Sciences, Regulatory, Clinical Operations, Market Access, Medical Affairs and Statistics
• Contribute to strategic initiatives and organizational improvements within Clinical Development
• Provide medical monitoring of study safety and ensure patient safety and on-time delivery of studies
• Lead the Clinical Matrix Team (CMT) for a program and serve as clinical contact for studies and stakeholders
• Stay abreast of advancements to maintain competitive edge and identify transformational opportunities
• Integrate input from scientific, clinical, regulatory, and commercial teams to inform Medicine Profiles and development decisions

Key requirements

• Medical Degree
• Postgraduate clinical training or specialty training in Internal Medicine, Pathology, or equivalent
• Experience in clinical trial conduct, medical monitoring, safety review and data interpretation
• Strong knowledge of clinical development processes, GCP, ICH guidelines, and global regulatory frameworks
• Ability to apply clinical judgment to support study design and patient safety in a structured development framework
• Experience in cross-functional matrix environments in pharma, biotech, or academia
• Strong scientific communication skills for translating data to insights
• Desirable: advanced specialty training and experience with regulatory submissions (IND/NDA/MAA) and KEEs

• leadership and influence
• collaboration in cross-functional teams
• clear scientific communication
• Clinical Development
• Regulatory Affairs
• Pharmacovigilance and safety monitoring

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