Principal Scientist – Analytics Team Lead

Overview

In this role you lead the PCA and MS analytics for a diverse biologics pipeline at the Biologics Research Center. You will manage a small team, drive innovative analytics strategy and ensure high-quality deliverables supporting candidate selection and clinical development. You work across a global matrix to enable multiple modalities, from antibodies to gene therapy vectors. This is a chance to shape cutting-edge analytical applications and build a collaborative, high-performing team.

Pay / Benefits

• comprehensive benefits package including health, life and disability benefits
• 401(k) with company contribution and match
• vacation, personal days, holidays, and other leaves
• variable pay / equity considerations
• on-site or flexible work options (location-based)

Responsibilities

• Develop and drive the PCA and MS analytics strategy for a diverse biologics portfolio, across multiple modalities
• Serve as senior analytics expert in project teams, ensuring high-quality deliverables
• Foster efficient processes, optimize capacity, and introduce new technologies
• Manage resources, project timelines, and customer expectations
• Provide leadership, guidance, and development opportunities to team members
• Promote collaboration, integrity, and a safe, empowering work environment

Key requirements

• PhD in biochemistry, biotechnology, or chemistry with 3+ years pharma experience
• 2+ years of people management experience
• Strong background in analyzing recombinant proteins (mAbs, multispecifics, therapeutic proteins) using MS, chromatography, capillary electrophoresis, and light scattering
• Experience with cutting-edge PCA characterization for novel biologics (AAV, ADCs, oligonucleotides, CAR-Ts)
• Experience with LC-MS (intact/reduced/subunit RPMS, peptide mapping, released glycans) and instrumentation (Orbitraps, QTOFs)
• Experience with data analysis workflows and report generation
• Proven leadership, coaching, and team development skills
• Excellent organizational and communication skills

• High flexibility
• Strong organizational and communication skills
• Team leadership and collaboration
• Mass spectrometry (MS) and PCA techniques
• Chromatography (SEC, HIC, IEX, RPC)
• Capillary electrophoresis (cIEF, CZE, CE-SDS)

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