Principal scientist

Company IconUCB S.A.
Location IconPrinces Risborough

Make your mark for patients About the role We are looking for a Principal Scientist - SPR and Biophysical Assays who is innovative, collaborative, and scientifically rigorous to join our team in In Vitro Pharmacology, based at o...Read More>>.

Posted: September 1st, 2026
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Senior Principal Scientist, Medicinal Chemistry & Strategy

Company IconSygnature Discovery Limited
Location Icon

Sygnature Discovery Limited is seeking an experienced Associate Principal Scientist / Principal Scientist for our Chemistry team at Alderley Park. You will lead medicinal chemistry programmes, shape project strategies, and mentor scientists across...Read More>>.

Posted: September 1st, 2026
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Associate Principal Scientist/Principal Scientist - Medicinal Chemistry

Company IconSygnature Discovery
Location IconMacclesfield

About Sygnature DiscoveryAt Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ scientists...Read More>>.

Posted: September 1st, 2026
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Associate Principal Scientist/Principal Scientist - Medicinal Chemistry

Company IconSygnature Discovery Limited
Location Icon

About Sygnature DiscoveryAt Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible.We’re...Read More>>.

Posted: September 1st, 2026
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Principal Scientist – SPR & Biophysical Assays (Hybrid)

Company IconUCB S.A.
Location IconPrinces Risborough

UCB is seeking a Principal Scientist for SPR and biophysical assays at our Slough, Berkshire campus to drive discovery programs.You will design, optimize, and lead complex SPR and biophysical studies, generate binding and kinetics data, and...Read More>>.

Posted: September 1st, 2026
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Principal Scientist - Cardiac Electrophysiology & Translational Ion Channels

Company IconIQVIA
Location IconCambridge

Are you the scientific leader who can bridge cutting-edge cardiac models with real-world drug discovery decisions?Have you built electrophysiology strategies, led multidisciplinary teams, and remained close enough to the scienc...Read More>>.

Posted: September 17th, 2026
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Associate Principal Scientist

Company IconEvotec SE
Location IconMacclesfield

We are currently recruiting for a Associate Principal Scientist, HT-Analytical Method Development to join our Analytical Sciences team based in Alderley Park. Role: Associate Principal Scientist (High Throughput ADME Method Develo...Read More>>.

Posted: October 1st, 2026
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Principal Scientist

Company IconHyper Recruitment Solutions Ltd
Location IconNorthern Ireland

Role OverviewAre you ready to take your career to the next level in the field of Structural Biology? A leading organisation in the life sciences industry is seeking a Principal Scientist in Structural Biology to join their dynamic team...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Translational Bioanalysis & Biomarkers

Company IconNucleome Therapeutics Ltd
Location IconOxford

Nucleome Therapeutics Ltd invites a Principal Scientist to lead translational bioanalysis and biomarker strategies for our autoimmune antibody programme. You will guide PK, ADA, PD and exploratory biomarker plans across discovery, preclinical and...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Process Engineering

Company IconBristol Myers Squibb
Location IconWirral

At Bristol Myers Squibb, our employees often ask, "Who are you working for?"- a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medi...Read More>>.

Posted: October 1st, 2026
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Principal Scientist

Company IconIpsen Biopharm Ltd
Location IconWales

Title:Principal Scientist Company:Ipsen Biopharm Ltd About Ipsen: Ipsen is a mid-sized global biopharmaceutical company with a focus on transformative medicines in three therapeutic areas: Oncology, Rare Disease and Neuroscience. Supported by n...Read More>>.

Posted: October 1st, 2026
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Principal Scientist

Company IconIpsen
Location IconWales

Principal Scientist - Cell Line Development & Upstream Process DevelopmentLocation: Wrexham, UK (Hybrid Working)Contract: PermanentTravel: Occasional travel (European)Shape the Future of Biologics at Ipsen...Read More>>.

Posted: October 1st, 2026
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Principal Scientist (Comp. Bio/ML) - Genomics

Company IconHelical
Location IconLondon

We're looking for a Principal Computational Scientist/Director to help translate our foundation models into impactful, real-world discovery workflows. In this role, you'll provide scientific leadership across model evaluation and applied use ca...Read More>>.

Posted: October 1st, 2026
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Principal Scientist

Company IconNexus Life Sciences
Location IconStone Cross

Principal Scientist - Analytical Location: Sandwich Salary: Up to £57,000 per annum Job Type: Permanent | Full‑time (37.5 hours) A leading UK scientific organisation is seeking an experienced Principal Scientist...Read More>>.

Posted: October 1st, 2026
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Associate Principal Scientist

Company IconEvotec
Location IconAlderley

We are currently recruiting for a Associate Principal Scientist, HT-Analytical Method Development to join our Analytical Sciences team based in Alderley Park. Role: Associate Principal Scientist (High Throughput ADME Method Development)...Read More>>.

Posted: October 1st, 2026
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Associate Principal Scientist

Company IconEvotec WD
Location Icon

We are currently recruiting for a Associate Principal Scientist, HT-Analytical Method Development to join our Analytical Sciences team based in Alderley Park.Role: Associate Principal Scientist (High Throughput ADME Method Development)...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Translational Bioanalysis and Biomarkers

Company IconNucleome Therapeutics Ltd
Location IconOxford

Overview of the role: Nucleome Therapeutics is entering a pivotal phase of pipeline expansion, translating its proprietary understanding of 3D gene regulation in disease into a growing portfolio of therapeutic programmes. To support th...Read More>>.

Posted: October 1st, 2026
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Translational Principal Scientist

Company IconRedx Pharma Plc
Location IconMacclesfield

Reporting directly to the Chief Scientific Officer, the Translational Principal Scientist will provide scientific, strategic, and operational leadership for translational research activities across clinical and late-stage discovery programmes....Read More>>.

Posted: October 1st, 2026
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Principal Scientist – Immunoassay

Company IconPlanet Pharma
Location IconFordham

Principal Scientist – Immunoassay Ready to lead the future of bioanalytical innovation? Join us as a Principal Scientist in Immunoassay, where your expertise can drive groundbreaking research in a dynamic, collaborative environment....Read More>>.

Posted: October 1st, 2026
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Senior Scientist/Associate Principal Scientist - Process Chemistry

Company IconDifferent Technologies Pty Ltd.
Location IconCardiff

Join a team that’s transforming drug development At CatSci, we partner with our clients to solve complex scientific problems and accelerate the delivery of life-changing medicines. We’re now looking for a Senior Scientist/ Ass...Read More>>.

Posted: October 1st, 2026
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Associate Principal Scientist, Medicinal Chemistry

Company IconPharmaron
Location IconHoddesdon

Associate Principal Scientist, Medicinal Chemistry Associate Principal Scientist, Medicinal Chemistry Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 25,000 employees wor...Read More>>.

Posted: October 2nd, 2026
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Senior Principal Scientist, Global Process Development

Company IconLonza Group Ltd.
Location IconSlough

Senior Principal Scientist, Global Process DevelopmentLocation: Slough, UK. The actual location of this job is in Slough, UK.Join our Global Process Development team as a senior scientific expert, where you will lead s...Read More>>.

Posted: October 3rd, 2026
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Principal Scientist – High-Throughput Bioprocess Technology Development

Company IconLonza Group Ltd.
Location IconSlough

Title: Principal Scientist – High-Throughput Bioprocess Technology DevelopmentLocation: SloughWe are seeking an experienced Principal Scientist to identify, evaluate and deploy emerging technologies that enable more controllable,...Read More>>.

Posted: October 3rd, 2026
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Principal Scientist, High-Throughput Bioprocess Automation

Company IconLonza Group Ltd.
Location IconSlough

Lonza is seeking a Principal Scientist to identify and deploy emerging technologies for controllable, automated high-throughput bioprocess models across Integrated Biologics R&D. The role blends technology development, bioengineering, experimental...Read More>>.

Posted: October 3rd, 2026
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Principal Scientist, Inflammation Research

Company Icon2420 MiroBio Ltd
Location IconOxford

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access...Read More>>.

Posted: October 3rd, 2026
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Principal Scientist - Assay Development

Company IconStem Recruitment
Location IconWhitehough

STEM Recruitment is working with a valued client in their search for a Principal Scientist - Assay Development to join their team in the Midlands.The Principal Scientist will lead scientific initiatives, provide strategic input, and oversee...Read More>>.

Posted: October 9th, 2026
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Principal Scientist in Jordanstown

Company IconEnergy Jobline CVL
Location IconNorthern Ireland

ROLE OVERVIEW Are you ready to take your career to the next level in the field of Structural Biology? A leading organisation in the life sciences industry is seeking a Principal Scientist in Structural Biology to join their dynamic team i...Read More>>.

Posted: October 11th, 2026
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Principal Scientist (PD/MSAT)

Company IconMytos
Location IconLondon

About UsAbout Us: You rarely get the chance to change an entire industry. But that's the position we find ourselves in. Join us, and you'll help scale cures to patients that need them sooner. We've developed fully-automated cell manu...Read More>>.

Posted: October 11th, 2026
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Principal Scientist

Company IconEssential Pharma Ltd
Location IconEgham

Essential Pharma is a global pharmaceutical company working to make a difference for patients in niche populations. Everything at Essential Pharma is driven by the fact that every patient matters. We are focused on developing and delivering medici...Read More>>.

Posted: October 11th, 2026
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Principal Scientist, Preclinical External Innovation

Company IconLifeArc
Location IconStevenage

Job Title: Principal Scientist, Preclinical External InnovationLocation: London, with travel to StevenageJob Type: Permanent with hybrid working (3 days in the office required)Closing date: 19 October 2026Agen...Read More>>.

Posted: October 12th, 2026
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Principal Scientist - PK/PD Leader

Company IconPharmaron
Location IconHoddesdon

About Pharmaron Pharmaron is a global contract research and manufacturing organization (CRO/CDMO)helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the UK, US, Chi...Read More>>.

Posted: October 12th, 2026
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PK/PD Modelling Leader | Principal Scientist

Company IconPharmaron
Location IconHoddesdon

Pharmaron is seeking an experienced PK/PD Leader to provide scientific leadership in pharmacokinetic/pharmacodynamic modelling and simulation across our global drug discovery and development organisation.You will design and deliver PK/PD st...Read More>>.

Posted: October 12th, 2026
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Principal Scientist, Anti-Infectives: Preclinical Lead

Company IconLifeArc
Location IconLondon

LifeArc in London, with travel to Stevenage, seeks a Principal Scientist, Preclinical Project Leadership in Anti-Infectives to lead and support preclinical programmes accelerating anti-infectives development, aligning with LifeArc’s AMR strategy...Read More>>.

Posted: October 13th, 2026
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Principal Scientist, Preclinical Project Leadership, Anti-Infectives

Company IconLifeArc
Location IconLondon

Job Title: Principal Scientist, Preclinical Project Leadership, Anti-InfectivesLocation: London, with travel to StevenageJob Type: Permanent with hybrid working (3 days in the office required) Closing date: 19 October 20...Read More>>.

Posted: October 13th, 2026
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Clinical Pharmacology Lead - Principal Scientist

Company IconRoche
Location IconWelwyn

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to th...Read More>>.

Posted: October 14th, 2026
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Principal Scientist, Immunogenicity and Ligand Binding Assays

Company IconModerna
Location IconOxford

The RoleJoining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients.This role sits at the forefro...Read More>>.

Posted: October 14th, 2026
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Lead Biostatistician & Principal Scientist, Clinical Trials

Company IconICON Clinical Research
Location IconReading

ICON plc in Reading, UK, seeks a Senior Principal Biostatistician to lead statistical methodologies for clinical studies, ensuring data integrity and regulatory compliance. The role oversees biostatistics workstreams, mentors junior statisticians,...Read More>>.

Posted: October 14th, 2026
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Principal Scientist, Preclinical Project Leadership, Rare Neurological Diseases

Company IconLifeArc
Location IconLondon

Job Title: Principal Scientist, Preclinical Project Leadership, Rare Neurological Diseases Location: London, with travel to Stevenage Job Type: Permanent with hybrid working (3 days in the office required) Closing da...Read More>>.

Posted: October 15th, 2026
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Principal Scientist, Functional Genomics

Company IconNovo Nordisk
Location IconOxford

Your impact starts here As Principal Scientist, Functional Genomics, you will combine cutting-edge biology, gene editing, and advanced screening approaches to uncover new therapeutic opportunities. You will develop and apply innovative, a...Read More>>.

Posted: October 15th, 2026
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Associate Principal Scientist

Company IconLonza
Location IconCambridge

Overview As an Associate Principal Scientist at Lonza, you will lead strategic scientific projects to advance biopharmaceutical process development and optimization. You collaborate across manufacturing, quality control, and regulato...Read More>>.

Posted: October 16th, 2026
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Principal Scientist PK/PD

Company IconUCB Group
Location IconBerkshire

Overview In this role you will lead the non-clinical PKPD strategy within the QCP function to enable quantitative translation from preclinical data to patient outcomes. You will work with cross-functional teams to shape drug candidat...Read More>>.

Posted: October 16th, 2026
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Principal Scientist II, Translational Biomarker Strategy Lead

Company IconNovartis
Location IconCambridge

Overview In this role you will lead and shape preclinical and translational biomarker strategies for DAx programs, guiding target validation to early clinical planning. You will act as the biomarker representative on project teams, c...Read More>>.

Posted: October 16th, 2026
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Principal Scientist PK/PD

Company IconUCB
Location IconSlough

Principal Scientist, Non-Clinical PKPD We are looking for a Principal Scientist, Non-Clinical PKPD, who is innovative and agile to join us in our Clinical Development Sciences Group, based at the R&D site in Slough, UK, then Windlesham...Read More>>.

Posted: September 21st, 2026
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Principal Scientist, Bioanalytical & Molecular Assays

Company IconModerna Therapeutics
Location IconHarwell

The RoleJoining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients. This role is based at Moderna's Harwell site...Read More>>.

Posted: October 3rd, 2026
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