Principal Scientist - Cardiac Electrophysiology & Translational Ion Channels

Company IconIQVIA
Location IconCambridge

Overview In this role you will shape and lead the cardiac electrophysiology and translational ion channel strategy across multiple drug discovery programs. You will bridge bench science with client-driven decision making, translating electr...Read More>>.

Posted: September 30th, 2026
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Senior Principal Scientist, Global Process Development

Company IconLonza
Location IconSlough

Overview In this Senior Principal Scientist role, you will drive strategic process development projects within Lonza’s global biologics network and lead cross-site collaborations. The position is site-based in Slough, with optional remote...Read More>>.

Posted: September 30th, 2026
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Principal Scientist, Functional Genomics

Company IconNovo Nordisk Pharma
Location Icon

Overview In this role you will lead and shape cutting-edge functional genomics efforts to identify and validate therapeutic targets. You will drive automation-friendly screening approaches and digital data strategies to scale experimentatio...Read More>>.

Posted: September 30th, 2026
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Principal Scientist, Biomarker Assay Development Bench Scientist

Company IconNovartis
Location IconCambridge

Overview As a Principal Scientist, you will lead bench research to design, develop, and qualify biomarker assays for preclinical and clinical programs across DAx. You will develop and implement ligand-binding assays (ELISA, MSD, immunoassay...Read More>>.

Posted: October 1st, 2026
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Principal Scientist PK/PD

Company IconUCB Group
Location IconBerkshire

Overview In this role you will lead the non-clinical PKPD strategy within the QCP function to enable quantitative translation from preclinical data to patient outcomes. You will work with cross-functional teams to shape drug candidates from...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Bioanalytical & Molecular Assays

Company IconModerna Therapeutics
Location Icon

Overview Join Moderna at the Harwell site to lead development of advanced molecular assays that support clinical endpoints across multiple programs. You will work across molecular biology, bioanalysis, genomics, informatics, and clinical de...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Pharmaceutical Development

Company IconIQVIA
Location IconCambridge

Overview In this Principal Scientist role, you will lead developability-focused science within a modern IQVIA Pharmaceutical Development function, combining physicochemical sciences, biopharmaceutics and AI-enabled approaches to anticipate...Read More>>.

Posted: October 1st, 2026
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Principal Scientist I/II, Oligonucleotide Chemistry & Innovation

Company IconNovartis
Location IconCambridge

Overview In this role you will advance Novartis’ xRNA platform by leading oligonucleotide chemistry development and cross-functional collaboration to drive RNA therapeutics from discovery through preclinical stages. You’ll mentor scient...Read More>>.

Posted: October 1st, 2026
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Principal scientist

Company IconUCB Group
Location IconBerkshire

Overview As Principal Scientist in In Vitro Pharmacology at UCB, you will drive SPR and biophysical assay data generation to support drug discovery programs. You’ll provide scientific leadership, influence project decisions, and help adva...Read More>>.

Posted: October 1st, 2026
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Principal Scientist MSAT

Company IconSRG Talent
Location IconDarlington

Overview In this MSAT-focused role, you lead complex biologics programs, guiding transfer and scale-up of bioprocesses into GMP manufacturing. You will partner with operations, quality and engineering to ensure robust, scalable processes th...Read More>>.

Posted: October 1st, 2026
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Principal Scientist

Company IconIpsen
Location Icon

Overview As Principal Scientist, you will lead Cell Line Development and Upstream Process Development for biologics, guiding projects from early stage to commercial manufacture. You will provide scientific leadership across CLD and USP, men...Read More>>.

Posted: October 1st, 2026
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Life Sciences Senior Principal Scientist

Company IconPepsico
Location IconLeicester

Overview In this role you will shape and govern the EMEA Life Sciences research portfolio, translating global science strategies into regionally relevant programs that drive growth, claims, and reputation. You will lead scientific platforms...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Operational Excellence

Company IconNovo Nordisk Pharma
Location Icon

Overview In this role you drive the continuous improvement of science delivery within TIM, optimising workflows and strengthening quality systems to enable efficient, scalable execution. You partner with cross-functional teams to accelerate...Read More>>.

Posted: October 1st, 2026
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Principal Scientist I/II, Study Quality and Compliance - Nonclinical Safety/Toxicology

Company IconNovartis
Location IconCambridge

Overview In this role you will provide scientific and operational support to the Study Quality and Compliance group within Toxicology (Preclinical Safety). You will ensure training records, CVs and job descriptions are maintained, and that...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Inflammation Research

Company IconGILEAD Sciences
Location Icon

Overview In this role, you lead a team of scientists focused on developing novel biologic therapies for autoimmune disease. You’ll oversee in vitro and in vivo pharmacology studies to support lead and early discovery programs, delivering...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist / Director – Computational Chemistry (IDD)

Company IconPharmaron Biologics
Location IconHoddesdon

Overview In this senior role you lead the Computational Sciences strategy within Pharmaron's Integrated Drug Discovery (IDD) programs, shaping design and optimization of multi-modality ligands. You guide cross-functional teams, drive AI-ena...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist, Translational Profiling Imaging

Company IconNovartis
Location IconCambridge

Overview In this role you lead a translational profiling group focused on advanced imaging and spatial biology to enable target discovery and validation across disease areas. You shape imaging capabilities and integrate multi-omics and mole...Read More>>.

Posted: October 1st, 2026
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Principal Scientist II, Translational Biomarker Strategy Lead

Company IconNovartis
Location IconCambridge

Overview In this role you will lead and shape preclinical and translational biomarker strategies for DAx programs, guiding target validation to early clinical planning. You will act as the biomarker representative on project teams, coordina...Read More>>.

Posted: October 1st, 2026
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Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory

Company IconNovartis
Location IconCambridge

Overview In this role you lead a biomarker assay development lab to enable translational decisions across discovery to clinical development. You will guide a high-performing team and collaborate with translational medicine, data science, an...Read More>>.

Posted: October 1st, 2026
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Principal Scientist II - Pharmacology

Company IconNovartis
Location IconCambridge

Overview In this role you lead the design and execution of in vivo anti-tumor efficacy and PK/PD studies to evaluate cancer drug candidates in CDX, PDX, and syngeneic models. You work within the Oncology Pharmacology team in Cambridge to de...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist / Assoc Director, Oncology Translational Research

Company IconNovartis
Location IconCambridge

Overview In this role you will lead the development and deployment of scalable digital pathology workflows and AI-enabled image analysis for oncology biomarkers. You’ll work with cross-site teams to advance HALO AI workflows and RareCyte...Read More>>.

Posted: October 1st, 2026
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Principal Scientist - Protein Mass Spectrometry

Company IconGSK
Location Icon

Overview In this role you apply protein mass spectrometry expertise to characterise biotherapeutics, guiding early-phase development and critical decisions on quality attributes. You’ll work across Discovery and CMC Development in a matri...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist, Clinical Biomarkers

Company IconIpsen
Location IconLondon

Overview As Clinical Biomarker Lead, you will define and drive biomarker strategies to enable data-driven decisions across Ipsen’s oncology and rare disease programs. You will partner with cross-functional teams to ensure scientifically r...Read More>>.

Posted: October 1st, 2026
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Principal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting)

Company IconNovartis
Location IconCambridge

Overview In this role you apply AI-driven strategies to advance clinical pharmacology support for transformative medicines. You will shape AI-enabled solutions across PKS/clinical pharmacology, accelerating deliverables and enabling data-dr...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Immunogenicity and Ligand Binding Assays

Company IconModerna Therapeutics
Location Icon

Overview In this role you will lead and hands-on oversee LBA-based bioanalysis for Moderna’s mRNA-LNP programs, enabling critical clinical decisions with rigorous science and regulatory compliance. You will drive immunogenicity and ADA/ne...Read More>>.

Posted: October 1st, 2026
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Principal Scientist

Company IconHyper Recruitment Solutions
Location IconEdinburgh

Overview In this Principal Scientist role, you will lead structural biology client projects, shaping project strategy and scientific output. You will apply X-ray Crystallography and Cryo-EM to support discovery programs while mentoring coll...Read More>>.

Posted: October 1st, 2026
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Principal Scientist – High-Throughput Bioprocess Technology Development 

Company IconLonza
Location IconSlough

Overview In this role you will drive automation across biopharma R&D and development, implementing and tuning automated workflows for key assays. You will work with cross-functional teams to integrate liquid handling systems, ELN, LIMS, and...Read More>>.

Posted: October 2nd, 2026
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Computational Biologics Design – Associate Principal Scientist

Company IconAstraZeneca
Location IconCambridge

Overview In this role you will lead in silico design for biologics across oncology, respiratory and cardiovascular areas, translating structural and experimental data into actionable design insights. You will work closely with discovery and...Read More>>.

Posted: October 3rd, 2026
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Principal Computational Scientist: Biology + ML Discovery

Company IconHelical
Location IconLondon

Helical is seeking a Principal Computational Scientist/Director to translate foundation models into real-world discovery workflows. You will lead model evaluation and applied use cases, partnering with research, Product and Business Development to...Read More>>.

Posted: September 29th, 2026
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Principal Scientist / Associate Director, Soft Materials Experimentation

Company IconLilasciences
Location IconCambridge

Your Impact at LILA Lila is hiring a Scientific Leader to build and run our experimental soft materials team, covering formulations, polymers, colloids, gels, emulsions, inks, adhesives, and coatings. You will take on a group of four s...Read More>>.

Posted: September 29th, 2026
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Principal Scientist, Functional Genomics

Company IconNovo Nordisk A/S
Location IconOxford

Select how often (in days) to receive an alert: Create Alert Principal Scientist, Functional Genomics Category: Research Location: Oxford, South East, GB Your impact starts here As Principal Scientist, F...Read More>>.

Posted: September 30th, 2026
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Principal Scientist (Comp. Bio/ML) - Genomics

Company IconHelical
Location Icon

We’re looking for a Principal Computational Scientist/Director to help translate our foundation models into impactful, real-world discovery workflows. In this role, you’ll provide scientific leadership across model evaluation and applied use c...Read More>>.

Posted: October 2nd, 2026
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Computational Biologics Design – Associate Principal Scientist

Company IconAstraZeneca plc
Location IconCambridge

Job Title: Computational Biologics Design – Associate Principal Scientist Location: Cambridge Salary: Competitive Introduction to role: Are you ready to harness AI and computational structu...Read More>>.

Posted: October 3rd, 2026
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Principal Scientist, Assay Development, Microscopy, Plant Physiology

Company IconCorriculo Ltd
Location IconBanbury

Principal Scientist, Assay Development, Microscopy, Plant PhysiologyAll the relevant skills, qualifications and experience that a successful applicant will need are listed in the following description.A Principal Scientist op...Read More>>.

Posted: October 4th, 2026
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Associate Principal Scientist, AI-Driven Biologics Design

Company IconAstraZeneca plc
Location IconCambridge

AstraZeneca plc in Cambridge is seeking an Associate Principal Scientist to lead in silico design for biologics, integrating AI and structural biology to shape oncology, respiratory and cardiovascular programs. You will build scalable analytics, d...Read More>>.

Posted: October 4th, 2026
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Principal scientist

Company IconUCB
Location IconSlough

We are looking for a Principal Scientist – SPR and Biophysical Assays who is innovative, collaborative, and scientifically rigorous to join our team in In Vitro Pharmacology, based at our UCB campus in Slough, Berkshir...Read More>>.

Posted: August 10th, 2026
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Principal Scientist – SPR & Biophysical Assays (Hybrid)

Company IconUCB
Location IconSlough

UCB is seeking a Principal Scientist for SPR and Biophysical Assays in In Vitro Pharmacology at our Slough campus. You will lead the design, optimization, and execution of SPR and biophysical assays to drive drug discovery, while mentoring junior...Read More>>.

Posted: August 10th, 2026
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Senior Principal Scientist, Molecular Assays & Genomics

Company IconModerna Therapeutics
Location IconOxford

Moderna Therapeutics is seeking a Principal Scientist to lead Bioanalytical & Molecular Assays at its Harwell site in Oxford. You will provide hands-on scientific leadership for the design, development, optimization, and deployment of advanced mol...Read More>>.

Posted: September 1st, 2026
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Senior Scientist II / Associate Principal Scientist – DMPK

Company IconVernalis (R&D) Limited
Location IconFen Ditton

Permanent About Vernalis Working within our fully equipped research laboratories in Cambridge, our established group of scientists are world leaders in multiple hit-ID technologies and structure-based drug discovery. Our...Read More>>.

Posted: September 15th, 2026
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Principal Scientist – Analytical

Company IconConcept Life Sciences Group
Location IconChapel en le Frith

Job Role: Principal Scientist – GMP AnalyticalSite: Chapel-en-le-FrithSalary:Competitive - DOEJob type: Permanent, full time (37.5 hrs per week) Overview Concept Life Sciences is seek...Read More>>.

Posted: September 21st, 2026
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Principal Scientist PK/PD

Company IconUCB
Location IconSlough

Principal Scientist, Non-Clinical PKPD We are looking for a Principal Scientist, Non-Clinical PKPD, who is innovative and agile to join us in our Clinical Development Sciences Group, based at the R&D site in Slough, UK, then Windlesham...Read More>>.

Posted: September 21st, 2026
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Principal Scientist – Developability & AI for Drug Delivery

Company IconIQVIA Argentina
Location IconFen Ditton

IQVIA Cambridge is seeking a Principal Scientist in Pharmaceutical Development to lead developability studies, integrate experimental and AI-enabled data, and guide candidate progression. The role blends scientific leadership with client-facing ac...Read More>>.

Posted: September 22nd, 2026
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Principal Scientist, Pharmaceutical Development

Company IconIQVIA Argentina
Location IconFen Ditton

Principal Scientist, Pharmaceutical Development Cambridge, United Kingdom | Full time | Office-based | R1565135 Are you an ambitious scientist with expertise in developability, drug delivery or pharmaceutical development, wit...Read More>>.

Posted: September 22nd, 2026
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Principal Scientist, Bioanalytical & Molecular Assays

Company IconBioSpace
Location IconOxford

The Role Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients. The Role Joining Moderna mea...Read More>>.

Posted: September 29th, 2026
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Senior Principal Scientist, Molecular Assays & Genomics

Company IconBioSpace
Location IconOxford

Moderna is seeking a senior scientist to lead the development and validation of molecular assays supporting clinical endpoints at our Harwell site in the UK. You will oversee end-to-end assay lifecycle, partner with cross-functional teams, and dri...Read More>>.

Posted: September 29th, 2026
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