Principal Scientist - Cardiac Electrophysiology & Translational Ion Channels

Company IconIQVIA
Location IconCambridge

Overview In this role you will shape and lead the cardiac electrophysiology and translational ion channel strategy across multiple drug discovery programs. You will bridge bench science with client-driven decision making, translating electr...Read More>>.

Posted: September 30th, 2026
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Principal Scientist, Biomarker Assay Development Bench Scientist

Company IconNovartis
Location IconCambridge

Overview As a Principal Scientist, you will lead bench research to design, develop, and qualify biomarker assays for preclinical and clinical programs across DAx. You will develop and implement ligand-binding assays (ELISA, MSD, immunoassay...Read More>>.

Posted: October 1st, 2026
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Principal Scientist I/II, Oligonucleotide Chemistry & Innovation

Company IconNovartis
Location IconCambridge

Overview In this role you will advance Novartis’ xRNA platform by leading oligonucleotide chemistry development and cross-functional collaboration to drive RNA therapeutics from discovery through preclinical stages. You’ll mentor scient...Read More>>.

Posted: October 1st, 2026
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Principal Scientist I/II, Study Quality and Compliance - Nonclinical Safety/Toxicology

Company IconNovartis
Location IconCambridge

Overview In this role you will provide scientific and operational support to the Study Quality and Compliance group within Toxicology (Preclinical Safety). You will ensure training records, CVs and job descriptions are maintained, and that...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist / Director – Computational Chemistry (IDD)

Company IconPharmaron Biologics
Location IconHoddesdon

Overview In this senior role you lead the Computational Sciences strategy within Pharmaron's Integrated Drug Discovery (IDD) programs, shaping design and optimization of multi-modality ligands. You guide cross-functional teams, drive AI-ena...Read More>>.

Posted: October 1st, 2026
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Principal Scientist II, Translational Biomarker Strategy Lead

Company IconNovartis
Location IconCambridge

Overview In this role you will lead and shape preclinical and translational biomarker strategies for DAx programs, guiding target validation to early clinical planning. You will act as the biomarker representative on project teams, coordina...Read More>>.

Posted: October 1st, 2026
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Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory

Company IconNovartis
Location IconCambridge

Overview In this role you lead a biomarker assay development lab to enable translational decisions across discovery to clinical development. You will guide a high-performing team and collaborate with translational medicine, data science, an...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist / Assoc Director, Oncology Translational Research

Company IconNovartis
Location IconCambridge

Overview In this role you will lead the development and deployment of scalable digital pathology workflows and AI-enabled image analysis for oncology biomarkers. You’ll work with cross-site teams to advance HALO AI workflows and RareCyte...Read More>>.

Posted: October 1st, 2026
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Principal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting)

Company IconNovartis
Location IconCambridge

Overview In this role you apply AI-driven strategies to advance clinical pharmacology support for transformative medicines. You will shape AI-enabled solutions across PKS/clinical pharmacology, accelerating deliverables and enabling data-dr...Read More>>.

Posted: October 1st, 2026
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Principal Data Scientist

Company IconFirst Achieve
Location IconLondon

Director of Recruitment - Tech and Sales - USA & EMEAWould you like to join an organisation where data is at the core of the business? Do you want to join a company where you will be backed by the founder to innovate?This company u...Read More>>.

Posted: June 6th, 2026
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Principal Data Scientist

Company IconHarnham
Location IconLondon

5 days ago Be among the first 25 applicantsGet AI-powered advice on this job and more exclusive features.This range is provided by Harnham. Your actual pay will be based on your skills and experience — talk with your recruiter to l...Read More>>.

Posted: June 6th, 2026
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Principal Data Scientist

Company IconWyatt Partners
Location Icon

Wyatt Partners are engaged to find a Principal Data Scientist for one of the most recognisable brands on the planet.This an opportunity to have a tangible impact on the company, and also make your mark in the way the company approaches data...Read More>>.

Posted: June 6th, 2026
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Senior Scientist II / Associate Principal Scientist – DMPK

Company IconVernalis (R&D) Limited
Location IconCambridge

Permanent About Vernalis Working within our fully equipped research laboratories in Cambridge, our established group of scientists are world leaders in multiple hit-ID technologies and structure-based drug discovery. Our...Read More>>.

Posted: June 12th, 2026
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Principal Data Scientist

Company IconBritish Airways PLC
Location IconLondon

A career without limitsAs the nation's flag carrier, we take great pride in connecting Britain with the world and the world with Britain.It's something we've been doing for over 100 years, ever since we launched the world's first...Read More>>.

Posted: July 29th, 2026
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Principal Scientist – SPR & Biophysical Assays (Hybrid)

Company IconUCB
Location IconSlough

UCB is seeking a Principal Scientist for SPR and Biophysical Assays in In Vitro Pharmacology at our Slough campus. You will lead the design, optimization, and execution of SPR and biophysical assays to drive drug discovery, while mentoring junior...Read More>>.

Posted: July 30th, 2026
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Senior Principal Scientist, Medicinal Chemistry & Strategy

Company IconSygnature Discovery Limited
Location Icon

Sygnature Discovery Limited is seeking an experienced Associate Principal Scientist / Principal Scientist for our Chemistry team at Alderley Park. You will lead medicinal chemistry programmes, shape project strategies, and mentor scientists across...Read More>>.

Posted: September 1st, 2026
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Principal Scientist – SPR & Biophysical Assays (Hybrid)

Company IconUCB S.A.
Location IconPrinces Risborough

UCB is seeking a Principal Scientist for SPR and biophysical assays at our Slough, Berkshire campus to drive discovery programs.You will design, optimize, and lead complex SPR and biophysical studies, generate binding and kinetics data, and...Read More>>.

Posted: September 1st, 2026
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Remote Senior Principal Scientist - Computational Chemistry Director

Company IconPharmaron
Location IconHoddesdon

Pharmaron is seeking a Senior Principal Scientist/Director – Computational Chemistry to lead design and optimization in Integrated Drug Discovery. This senior role requires exceptional scientific expertise and client engagement to drive multi-mo...Read More>>.

Posted: September 9th, 2026
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Principal Analytical Scientist

Company IconSingular: Building Brilliant Biotechs
Location IconChapel en le Frith

You are an experienced analytical scientist with deep expertise in chromatography and analytical method development.You want to work in a senior, highly visible role where you can influence analytical strategy, remain close to the scienc...Read More>>.

Posted: September 17th, 2026
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Principal Scientist, Process Chemistry - Late Stage Development

Company IconPharmaron
Location IconHoddesdon

Principal Scientist, Process Chemistry - Late-Stage DevelopmentLocation: Hoddesdon, HertfordshireDepartment: Process ChemistryPharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. Wit...Read More>>.

Posted: September 20th, 2026
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Senior Principal Scientist, Late-Stage Process Chemistry

Company IconPharmaron
Location IconHoddesdon

Pharmaron Hoddesdon seeks a Principal Scientist to lead late-stage process chemistry, overseeing development, scale-up and technology transfer to GMP manufacturing for small‑molecule APIs. You will work with clients and cross-functional teams to...Read More>>.

Posted: September 21st, 2026
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Principal Data Scientist

Company IconDigital Futures
Location IconLondon

Digital Futures is seeking a Principal Data Scientist to lead high‑value analytical and modelling work, turning complex data into insights and AI models that drive client outcomes. The role combines hands‑on modelling with technical leaders...Read More>>.

Posted: September 22nd, 2026
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Principal Data Scientist

Company IconThe BDPN
Location IconLondon

Location: Dublin, Ireland, IE, D01 K840 London, GB, EC2V 7AD Company: Paysafe Paysafe is a leading payments platform with an extensive track record of serving merchants and consumers in the global entertainment secto...Read More>>.

Posted: September 26th, 2026
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Principal Staff Scientist

Company IconGenome Research Limited (GRL)
Location IconHinxton

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life‑changing science to solve some of humanity’s greatest challenges. We are looking for a Principal Staff...Read More>>.

Posted: September 27th, 2026
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Principal Computational Scientist: Biology + ML Discovery

Company IconHelical
Location IconLondon

Helical is seeking a Principal Computational Scientist/Director to translate foundation models into real-world discovery workflows. You will lead model evaluation and applied use cases, partnering with research, Product and Business Development to...Read More>>.

Posted: October 1st, 2026
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Principal Scientist: Cell Line & Upstream Process (Hybrid)

Company IconIpsen Biopharm Ltd
Location IconWales

Ipsen Biopharm Ltd seeks a Principal Scientist to lead Cell Line Development and Upstream Process Development for biologics. You will guide programmes from candidate selection to commercial manufacturing, providing technical leadership and mentori...Read More>>.

Posted: October 1st, 2026
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Senior Scientist/Associate Principal Scientist - Process Chemistry

Company IconDifferent Technologies Pty Ltd.
Location IconCardiff

Join a team that’s transforming drug development At CatSci, we partner with our clients to solve complex scientific problems and accelerate the delivery of life-changing medicines. We’re now looking for a Senior Scientist/ Ass...Read More>>.

Posted: October 1st, 2026
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Principal Clinical Scientist

Company IconAlignerr Corp.
Location IconBirmingham

Principal Clinical Scientist (AI Training)About The RoleWhat if your decades of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory submissions, and patient outcomes? We're looking...Read More>>.

Posted: October 9th, 2026
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Senior Principal Scientist, Molecular Assays & Genomics

Company IconModerna Therapeutics
Location IconOxford

Moderna Therapeutics is seeking a Principal Scientist to lead Bioanalytical & Molecular Assays at its Harwell site in Oxford. You will provide hands-on scientific leadership for the design, development, optimization, and deployment of advanced mol...Read More>>.

Posted: September 1st, 2026
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Principal Data Scientist

Company IconAWTG Ltd.
Location Icon

Role overview The Principal Data Scientist will lead significant data science work across AWTG and client programmes, shaping technical direction, standards and delivery approaches. The role requires deep expertise in data science, str...Read More>>.

Posted: September 21st, 2026
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Principal Scientist PK/PD

Company IconUCB
Location IconSlough

Principal Scientist, Non-Clinical PKPD We are looking for a Principal Scientist, Non-Clinical PKPD, who is innovative and agile to join us in our Clinical Development Sciences Group, based at the R&D site in Slough, UK, then Windlesham...Read More>>.

Posted: September 21st, 2026
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