Principal Scientist - Cardiac Electrophysiology & Translational Ion Channels

Company IconIQVIA
Location IconCambridge

Overview In this role you will shape and lead the cardiac electrophysiology and translational ion channel strategy across multiple drug discovery programs. You will bridge bench science with client-driven decision making, translating electr...Read More>>.

Posted: September 30th, 2026
View salary & More Info

Principal Scientist, Biomarker Assay Development Bench Scientist

Company IconNovartis
Location IconCambridge

Overview As a Principal Scientist, you will lead bench research to design, develop, and qualify biomarker assays for preclinical and clinical programs across DAx. You will develop and implement ligand-binding assays (ELISA, MSD, immunoassay...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist I/II, Oligonucleotide Chemistry & Innovation

Company IconNovartis
Location IconCambridge

Overview In this role you will advance Novartis’ xRNA platform by leading oligonucleotide chemistry development and cross-functional collaboration to drive RNA therapeutics from discovery through preclinical stages. You’ll mentor scient...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist I/II, Study Quality and Compliance - Nonclinical Safety/Toxicology

Company IconNovartis
Location IconCambridge

Overview In this role you will provide scientific and operational support to the Study Quality and Compliance group within Toxicology (Preclinical Safety). You will ensure training records, CVs and job descriptions are maintained, and that...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Principal Scientist / Director – Computational Chemistry (IDD)

Company IconPharmaron Biologics
Location IconHoddesdon

Overview In this senior role you lead the Computational Sciences strategy within Pharmaron's Integrated Drug Discovery (IDD) programs, shaping design and optimization of multi-modality ligands. You guide cross-functional teams, drive AI-ena...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist II, Translational Biomarker Strategy Lead

Company IconNovartis
Location IconCambridge

Overview In this role you will lead and shape preclinical and translational biomarker strategies for DAx programs, guiding target validation to early clinical planning. You will act as the biomarker representative on project teams, coordina...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory

Company IconNovartis
Location IconCambridge

Overview In this role you lead a biomarker assay development lab to enable translational decisions across discovery to clinical development. You will guide a high-performing team and collaborate with translational medicine, data science, an...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Principal Scientist / Assoc Director, Oncology Translational Research

Company IconNovartis
Location IconCambridge

Overview In this role you will lead the development and deployment of scalable digital pathology workflows and AI-enabled image analysis for oncology biomarkers. You’ll work with cross-site teams to advance HALO AI workflows and RareCyte...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting)

Company IconNovartis
Location IconCambridge

Overview In this role you apply AI-driven strategies to advance clinical pharmacology support for transformative medicines. You will shape AI-enabled solutions across PKS/clinical pharmacology, accelerating deliverables and enabling data-dr...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist PK/PD

Company IconUCB
Location IconSlough

Principal Scientist, Non-Clinical PKPD We are looking for a Principal Scientist, Non-Clinical PKPD, who is innovative and agile to join us in our Clinical Development Sciences Group, based at the R&D site in Slough, UK, then Windlesham...Read More>>.

Posted: June 6th, 2026
View salary & More Info

Senior Scientist II / Associate Principal Scientist – DMPK

Company IconVernalis (R&D) Limited
Location IconCambridge

Permanent About Vernalis Working within our fully equipped research laboratories in Cambridge, our established group of scientists are world leaders in multiple hit-ID technologies and structure-based drug discovery. Our...Read More>>.

Posted: June 12th, 2026
View salary & More Info

Principal Scientist – SPR & Biophysical Assays (Hybrid)

Company IconUCB
Location IconSlough

UCB is seeking a Principal Scientist for SPR and Biophysical Assays in In Vitro Pharmacology at our Slough campus. You will lead the design, optimization, and execution of SPR and biophysical assays to drive drug discovery, while mentoring junior...Read More>>.

Posted: July 30th, 2026
View salary & More Info

Principal Scientist – Analytical

Company IconConcept Life Sciences Group
Location IconChapel en le Frith

Job Role: Principal Scientist – GMP AnalyticalSite: Chapel-en-le-FrithSalary:Competitive - DOEJob type: Permanent, full time (37.5 hrs per week) Overview Concept Life Sciences is seek...Read More>>.

Posted: August 20th, 2026
View salary & More Info

MSAT Principal Scientist – Global Tech Transfer Lead

Company IconQCS Staffing
Location Icon

The MSAT Principal Scientist role at a leading speciality pharmaceutical company in the UK seeks an expert to lead site-to-site technology transfers across manufacturing, QC testing, and packaging, ensuring seamless transitions.You will dri...Read More>>.

Posted: September 1st, 2026
View salary & More Info

Principal scientist

Company IconUCB S.A.
Location IconPrinces Risborough

Make your mark for patients About the role We are looking for a Principal Scientist - SPR and Biophysical Assays who is innovative, collaborative, and scientifically rigorous to join our team in In Vitro Pharmacology, based at o...Read More>>.

Posted: September 1st, 2026
View salary & More Info

Senior Principal Scientist, Medicinal Chemistry & Strategy

Company IconSygnature Discovery Limited
Location Icon

Sygnature Discovery Limited is seeking an experienced Associate Principal Scientist / Principal Scientist for our Chemistry team at Alderley Park. You will lead medicinal chemistry programmes, shape project strategies, and mentor scientists across...Read More>>.

Posted: September 1st, 2026
View salary & More Info

MSAT Principal Scientist

Company IconQCS Staffing
Location Icon

MSAT Principal Scientist – Permanent – Life SciencesOur client, a speciality pharmaceutical company based in the South of the UK are looking for an MSAT Principal Scientist. Experts in their field they have a focus o...Read More>>.

Posted: September 1st, 2026
View salary & More Info

Principal Scientist – Structural Biology

Company IconConcept Life Sciences Group
Location IconCity of Edinburgh

Principal Scientist – Structural BiologyJob Role: Principal Scientist – Structural BiologySite:EdinburghSalary: Competitive - DOEConcept Life Sciences seeks a Principal Scientist in Structural Biology to hel...Read More>>.

Posted: September 1st, 2026
View salary & More Info

Associate Principal Scientist/Principal Scientist - Medicinal Chemistry

Company IconSygnature Discovery
Location IconMacclesfield

About Sygnature DiscoveryAt Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. We’re 700+ scientists...Read More>>.

Posted: September 1st, 2026
View salary & More Info

Associate Principal Scientist/Principal Scientist - Medicinal Chemistry

Company IconSygnature Discovery Limited
Location Icon

About Sygnature DiscoveryAt Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible.We’re...Read More>>.

Posted: September 1st, 2026
View salary & More Info

Principal Scientist – SPR & Biophysical Assays (Hybrid)

Company IconUCB S.A.
Location IconPrinces Risborough

UCB is seeking a Principal Scientist for SPR and biophysical assays at our Slough, Berkshire campus to drive discovery programs.You will design, optimize, and lead complex SPR and biophysical studies, generate binding and kinetics data, and...Read More>>.

Posted: September 1st, 2026
View salary & More Info

Chemistry Principal Scientist

Company IconEurofins UK Food Testing
Location IconLinlithgow

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the fo...Read More>>.

Posted: September 1st, 2026
View salary & More Info

Principal Scientist, Process Chemistry - Late Stage Development

Company IconPharmaron
Location IconHoddesdon

Principal Scientist, Process Chemistry - Late-Stage DevelopmentLocation: Hoddesdon, HertfordshireDepartment: Process ChemistryPharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. Wit...Read More>>.

Posted: September 20th, 2026
View salary & More Info

Senior Principal Scientist, Late-Stage Process Chemistry

Company IconPharmaron
Location IconHoddesdon

Pharmaron Hoddesdon seeks a Principal Scientist to lead late-stage process chemistry, overseeing development, scale-up and technology transfer to GMP manufacturing for small‑molecule APIs. You will work with clients and cross-functional teams to...Read More>>.

Posted: September 21st, 2026
View salary & More Info

Senior Principal Scientist, Molecular Assays & Genomics

Company IconBioSpace
Location IconOxford

Moderna is seeking a senior scientist to lead the development and validation of molecular assays supporting clinical endpoints at our Harwell site in the UK. You will oversee end-to-end assay lifecycle, partner with cross-functional teams, and dri...Read More>>.

Posted: September 29th, 2026
View salary & More Info

Associate Principal Scientist – In Vivo Pharmacology

Company IconBarrington James Limited
Location IconNottingham

About the Role We're seeking an experienced Associate Principal Scientist with expertise in kidney disease to join the In Vivo Pharmacology team, providing scientific leadership across complex, client-sponsored drug discovery programme...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist: Translational Biomarkers & Data

Company IconHyper Recruitment Solutions Ltd
Location IconWindsor

Hyper Recruitment Solutions Ltd is seeking a Principal Scientist for a leading pharmaceutical company in the Berkshire area. You will drive translational research, design and deliver translational data to underpin biomarker and quantitative pharma...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist, Translational Bioanalysis & Biomarkers

Company IconNucleome Therapeutics Ltd
Location IconOxford

Nucleome Therapeutics Ltd invites a Principal Scientist to lead translational bioanalysis and biomarker strategies for our autoimmune antibody programme. You will guide PK, ADA, PD and exploratory biomarker plans across discovery, preclinical and...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Principal Scientist / Associate Director

Company IconSygnature Discovery
Location IconGlasgow

About Sygnature Discovery At Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible. About Sygnature Dis...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Principal Scientist / Associate Director

Company IconSygnature Discovery Limited
Location IconGlasgow

About Sygnature DiscoveryAt Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible.We’re 700+ scientist...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Ion Channel Pharmacology Lead - Sr Principal Scientist/AD

Company IconSygnature Discovery
Location IconGlasgow

Sygnature Discovery in Glasgow seeks a Senior Principal Scientist / Associate Director to provide scientific, strategic and operational leadership within the Electrophysiology & Cellular Pharmacology group. You will steer a portfolio of electrophy...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Associate Principal Scientist – In Vivo Pharmacology (Kidney Disease)

Company IconBarrington James
Location IconNottingham

Join a well-established, contract drug discovery organisation as they expand their In Vivo Pharmacology team. With no competing internal programmes, this is a chance to shape science that matters, working directly with biotech and pharma client...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Lead Principal Scientist: Strategic Research & Mentoring

Company IconWestin Par
Location IconStone Cross

Westin Par is seeking two experienced Principal Scientists to lead strategic research programmes in a senior capacity within a leading scientific organisation. You will influence scientific strategy, mentor teams and stay hands-on with cutting-edg...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist, Translational Bioanalysis and Biomarkers

Company IconNucleome Therapeutics Ltd
Location IconOxford

Overview of the role: Nucleome Therapeutics is entering a pivotal phase of pipeline expansion, translating its proprietary understanding of 3D gene regulation in disease into a growing portfolio of therapeutic programmes. To support th...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Principal Scientist: Ion Channel Pharmacology Leader

Company IconSygnature Discovery Limited
Location IconGlasgow

Sygnature Discovery Limited in Glasgow is seeking a Senior Principal Scientist / Associate Director to lead the Electrophysiology & Cellular Pharmacology group and drive strategic and operational delivery for biotechnology and pharmaceutical clien...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist: Cell Line & Upstream Process (Hybrid)

Company IconIpsen Biopharm Ltd
Location IconWales

Ipsen Biopharm Ltd seeks a Principal Scientist to lead Cell Line Development and Upstream Process Development for biologics. You will guide programmes from candidate selection to commercial manufacturing, providing technical leadership and mentori...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Scientist/Associate Principal Scientist - Process Chemistry

Company IconDifferent Technologies Pty Ltd.
Location IconCardiff

Join a team that’s transforming drug development At CatSci, we partner with our clients to solve complex scientific problems and accelerate the delivery of life-changing medicines. We’re now looking for a Senior Scientist/ Ass...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Scientist/Associate Principal Scientist - Process Chemistry

Company IconCatsci Ltd
Location IconCardiff

Join a team that’s transforming drug developmentAt CatSci, we partner with our clients to solve complex scientific problems and accelerate the delivery of life-changing medicines. We’re now looking for a Senior Scientist/ Associate Pr...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Computational Scientist: Biology + ML Discovery

Company IconHelical
Location IconLondon

Helical is seeking a Principal Computational Scientist/Director to translate foundation models into real-world discovery workflows. You will lead model evaluation and applied use cases, partnering with research, Product and Business Development to...Read More>>.

Posted: September 29th, 2026
View salary & More Info
1 2 3 4 … 12