Principal Data Scientist

Company IconAristocrat Technologies
Location IconLondon

Overview As Principal Data Scientist, you will drive high-impact, end-to-end data initiatives to boost player engagement and business outcomes. You’ll lead modeling and experimentation across complex systems, collaborating with game teams...Read More>>.

Posted: September 30th, 2026
View salary & More Info

Principal Scientist - Cardiac Electrophysiology & Translational Ion Channels

Company IconIQVIA
Location IconCambridge

Overview In this role you will shape and lead the cardiac electrophysiology and translational ion channel strategy across multiple drug discovery programs. You will bridge bench science with client-driven decision making, translating electr...Read More>>.

Posted: September 30th, 2026
View salary & More Info

Senior Principal Scientist, Global Process Development

Company IconLonza
Location IconSlough

Overview In this Senior Principal Scientist role, you will drive strategic process development projects within Lonza’s global biologics network and lead cross-site collaborations. The position is site-based in Slough, with optional remote...Read More>>.

Posted: September 30th, 2026
View salary & More Info

Principal Data Scientist

Company IconFaculty
Location IconLondon

Overview Enthusiastic Principal Data Scientist who leads highly technical, high-impact AI projects for top clients in regulated sectors. You set technical direction for the data science team, mentor colleagues, and elevate the practice thro...Read More>>.

Posted: September 30th, 2026
View salary & More Info

Principal Data Scientist

Company IconVortexa
Location IconLondon

Overview As Principal Data Scientist at Vortexa, you lead high-impact data science work on frontier energy problems, shaping production-grade AI/ML solutions. You collaborate with analysts, engineers, traders, and regulators to ensure relia...Read More>>.

Posted: September 30th, 2026
View salary & More Info

Principal Scientist, Biomarker Assay Development Bench Scientist

Company IconNovartis
Location IconCambridge

Overview As a Principal Scientist, you will lead bench research to design, develop, and qualify biomarker assays for preclinical and clinical programs across DAx. You will develop and implement ligand-binding assays (ELISA, MSD, immunoassay...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist, Bioanalytical & Molecular Assays

Company IconModerna Therapeutics
Location Icon

Overview Join Moderna at the Harwell site to lead development of advanced molecular assays that support clinical endpoints across multiple programs. You will work across molecular biology, bioanalysis, genomics, informatics, and clinical de...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist, Pharmaceutical Development

Company IconIQVIA
Location IconCambridge

Overview In this Principal Scientist role, you will lead developability-focused science within a modern IQVIA Pharmaceutical Development function, combining physicochemical sciences, biopharmaceutics and AI-enabled approaches to anticipate...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist I/II, Oligonucleotide Chemistry & Innovation

Company IconNovartis
Location IconCambridge

Overview In this role you will advance Novartis’ xRNA platform by leading oligonucleotide chemistry development and cross-functional collaboration to drive RNA therapeutics from discovery through preclinical stages. You’ll mentor scient...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Research Scientist

Company IconKLA-Tencor
Location IconNewport

Overview In this role you will drive the conception and hands-on development of next‑generation plasma process technologies for challenging semiconductor manufacturing problems. You will lead hardware and process solutions, advancing plas...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Staff Scientist

Company IconWellcome Sanger Institute
Location IconHinxton

Overview In this role you lead AI/ML strategy for the Human Genetics Programme, shaping analytical methods across large-scale multiomic and clinical data. You will work with statisticians, computational scientists, and analysts to develop p...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal scientist

Company IconUCB Group
Location IconSlough

Overview As Principal Scientist in In Vitro Pharmacology at UCB, you will drive SPR and biophysical assay data generation to support drug discovery programs. You’ll provide scientific leadership, influence project decisions, and help adva...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist

Company IconIpsen
Location Icon

Overview As Principal Scientist, you will lead Cell Line Development and Upstream Process Development for biologics, guiding projects from early stage to commercial manufacture. You will provide scientific leadership across CLD and USP, men...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist I/II, Study Quality and Compliance - Nonclinical Safety/Toxicology

Company IconNovartis
Location IconCambridge

Overview In this role you will provide scientific and operational support to the Study Quality and Compliance group within Toxicology (Preclinical Safety). You will ensure training records, CVs and job descriptions are maintained, and that...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist, Inflammation Research

Company IconGILEAD Sciences
Location Icon

Overview In this role, you lead a team of scientists focused on developing novel biologic therapies for autoimmune disease. You’ll oversee in vitro and in vivo pharmacology studies to support lead and early discovery programs, delivering...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Principal Scientist / Director – Computational Chemistry (IDD)

Company IconPharmaron Biologics
Location IconHoddesdon

Overview In this senior role you lead the Computational Sciences strategy within Pharmaron's Integrated Drug Discovery (IDD) programs, shaping design and optimization of multi-modality ligands. You guide cross-functional teams, drive AI-ena...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Principal Scientist, Translational Profiling Imaging

Company IconNovartis
Location IconCambridge

Overview In this role you lead a translational profiling group focused on advanced imaging and spatial biology to enable target discovery and validation across disease areas. You shape imaging capabilities and integrate multi-omics and mole...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist II, Translational Biomarker Strategy Lead

Company IconNovartis
Location IconCambridge

Overview In this role you will lead and shape preclinical and translational biomarker strategies for DAx programs, guiding target validation to early clinical planning. You will act as the biomarker representative on project teams, coordina...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory

Company IconNovartis
Location IconCambridge

Overview In this role you lead a biomarker assay development lab to enable translational decisions across discovery to clinical development. You will guide a high-performing team and collaborate with translational medicine, data science, an...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist II - Pharmacology

Company IconNovartis
Location IconCambridge

Overview In this role you lead the design and execution of in vivo anti-tumor efficacy and PK/PD studies to evaluate cancer drug candidates in CDX, PDX, and syngeneic models. You work within the Oncology Pharmacology team in Cambridge to de...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Senior Principal Scientist / Assoc Director, Oncology Translational Research

Company IconNovartis
Location IconCambridge

Overview In this role you will lead the development and deployment of scalable digital pathology workflows and AI-enabled image analysis for oncology biomarkers. You’ll work with cross-site teams to advance HALO AI workflows and RareCyte...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist PK/PD

Company IconUCB Group
Location IconSlough

Overview In this role you will lead the non-clinical PKPD strategy within the QCP function to enable quantitative translation from preclinical data to patient outcomes. You will work with cross-functional teams to shape drug candidates from...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting)

Company IconNovartis
Location IconCambridge

Overview In this role you apply AI-driven strategies to advance clinical pharmacology support for transformative medicines. You will shape AI-enabled solutions across PKS/clinical pharmacology, accelerating deliverables and enabling data-dr...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist, Immunogenicity and Ligand Binding Assays

Company IconModerna Therapeutics
Location Icon

Overview In this role you will lead and hands-on oversee LBA-based bioanalysis for Moderna’s mRNA-LNP programs, enabling critical clinical decisions with rigorous science and regulatory compliance. You will drive immunogenicity and ADA/ne...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist

Company IconHyper Recruitment Solutions
Location IconEdinburgh

Overview In this Principal Scientist role, you will lead structural biology client projects, shaping project strategy and scientific output. You will apply X-ray Crystallography and Cryo-EM to support discovery programs while mentoring coll...Read More>>.

Posted: October 1st, 2026
View salary & More Info

Principal Scientist – High-Throughput Bioprocess Technology Development 

Company IconLonza
Location IconSlough

Overview In this role you will drive automation across biopharma R&D and development, implementing and tuning automated workflows for key assays. You will work with cross-functional teams to integrate liquid handling systems, ELN, LIMS, and...Read More>>.

Posted: October 2nd, 2026
View salary & More Info

Principal Scientist – Analytics Team Lead

Company IconNovartis
Location IconCambridge

Overview In this role you lead the PCA and MS analytics for a diverse biologics pipeline at the Biologics Research Center. You will manage a small team, drive innovative analytics strategy and ensure high-quality deliverables supporting can...Read More>>.

Posted: October 8th, 2026
View salary & More Info

Principal Data Scientist

Company IconMarshmallow
Location IconLondon

Overview As Principal Data Scientist in Claims, you lead data science initiatives across fraud risk and automated claims, shaping scalable ML and Generative AI solutions. You will collaborate with Product and Engineering to align technical...Read More>>.

Posted: October 8th, 2026
View salary & More Info

Principal Clinical Scientist

Company IconCSL
Location IconMaidenhead

Principal Clinical Scientist(Senior Clinical Scientist level also considered)The RoleWe're looking for a clinical scientist — someone who has been the scientific lead for clinical studies before,...Read More>>.

Posted: October 8th, 2026
View salary & More Info

Principal Data Scientist

Company IconAutoTrader UK
Location IconManchester

Overview In this role, you will steer Autotrader’s data science direction as a principal within cross-functional squads. You’ll shape ML-driven data products, mentor peers, and collaborate with engineers to deliver impactful solutions....Read More>>.

Posted: October 10th, 2026
View salary & More Info

Associate Principal Scientist

Company IconLonza
Location IconCambridge

Overview As an Associate Principal Scientist at Lonza, you will lead strategic scientific projects to advance biopharmaceutical process development and optimization. You collaborate across manufacturing, quality control, and regulatory affa...Read More>>.

Posted: October 16th, 2026
View salary & More Info

Senior Principal Scientist, Molecular Assays & Genomics

Company IconModerna Therapeutics
Location IconOxford

Moderna Therapeutics is seeking a Principal Scientist to lead Bioanalytical & Molecular Assays at its Harwell site in Oxford. You will provide hands-on scientific leadership for the design, development, optimization, and deployment of advanced mol...Read More>>.

Posted: September 1st, 2026
View salary & More Info

Remote Senior Principal Scientist - Computational Chemistry Director

Company IconPharmaron
Location IconHoddesdon

Pharmaron is seeking a Senior Principal Scientist/Director – Computational Chemistry to lead design and optimization in Integrated Drug Discovery. This senior role requires exceptional scientific expertise and client engagement to drive multi-mo...Read More>>.

Posted: September 9th, 2026
View salary & More Info

Senior Scientist II / Associate Principal Scientist – DMPK

Company IconVernalis (R&D) Limited
Location IconCambridge

Permanent About Vernalis Working within our fully equipped research laboratories in Cambridge, our established group of scientists are world leaders in multiple hit-ID technologies and structure-based drug discovery. Our...Read More>>.

Posted: September 15th, 2026
View salary & More Info

Principal Analytical Scientist

Company IconSingular: Building Brilliant Biotechs
Location IconChapel en le Frith

You are an experienced analytical scientist with deep expertise in chromatography and analytical method development.You want to work in a senior, highly visible role where you can influence analytical strategy, remain close to the scienc...Read More>>.

Posted: September 21st, 2026
View salary & More Info

Principal Data Scientist

Company IconAWTG Ltd.
Location Icon

Role overview The Principal Data Scientist will lead significant data science work across AWTG and client programmes, shaping technical direction, standards and delivery approaches. The role requires deep expertise in data science, str...Read More>>.

Posted: September 21st, 2026
View salary & More Info

Principal Scientist PK/PD

Company IconUCB
Location IconSlough

Principal Scientist, Non-Clinical PKPD We are looking for a Principal Scientist, Non-Clinical PKPD, who is innovative and agile to join us in our Clinical Development Sciences Group, based at the R&D site in Slough, UK, then Windlesham...Read More>>.

Posted: September 21st, 2026
View salary & More Info

Lead Biostatistician & Principal Scientist, Clinical Trials

Company IconICON Clinical Research
Location IconReading

ICON plc in Reading, UK, seeks a Senior Principal Biostatistician to lead statistical methodologies for clinical studies, ensuring data integrity and regulatory compliance. The role oversees biostatistics workstreams, mentors junior statisticians,...Read More>>.

Posted: October 14th, 2026
View salary & More Info

Principal Scientist, Preclinical Project Leadership, Rare Neurological Diseases

Company IconLifeArc
Location IconLondon

Job Title: Principal Scientist, Preclinical Project Leadership, Rare Neurological Diseases Location: London, with travel to Stevenage Job Type: Permanent with hybrid working (3 days in the office required) Closing da...Read More>>.

Posted: October 15th, 2026
View salary & More Info
1 2 3 … 9