Principal Clinical Scientist

Company IconCSL Behring
Location IconMaidenhead

Principal Clinical Scientist(Senior Clinical Scientist level also considered)The RoleWe're looking for a clinical scientist someone who has been the scientific lead for clinical studies before, from proto...Read More>>.

Posted: September 30th, 2026
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Principal Data Scientist & Machine Learning Researcher

Company IconHackajob Ltd
Location IconGloucester

Our client is a major defence and aerospace company.Date Posted:2026-05-28Country:United KingdomLocation:Gloucester, South GloucestershirePosition Role Type:Hybrid...Read More>>.

Posted: August 26th, 2026
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Principal Data Scientist, Experimentation

Company IconTripAdvisor
Location IconLondon

Overview As a Principal Data Scientist at Tripadvisor, you will lead experimentation strategy across the organization, raising the bar on measurement quality and decision-making. You’ll build self-service standards, tooling, and protocols...Read More>>.

Posted: September 30th, 2026
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Principal Data Scientist

Company IconAristocrat Technologies
Location IconLondon

Overview As Principal Data Scientist, you will drive high-impact, end-to-end data initiatives to boost player engagement and business outcomes. You’ll lead modeling and experimentation across complex systems, collaborating with game teams...Read More>>.

Posted: September 30th, 2026
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Principal Scientist - Cardiac Electrophysiology & Translational Ion Channels

Company IconIQVIA
Location IconCambridge

Overview In this role you will shape and lead the cardiac electrophysiology and translational ion channel strategy across multiple drug discovery programs. You will bridge bench science with client-driven decision making, translating electr...Read More>>.

Posted: September 30th, 2026
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Senior Principal Scientist, Global Process Development

Company IconLonza
Location IconSlough

Overview In this Senior Principal Scientist role, you will drive strategic process development projects within Lonza’s global biologics network and lead cross-site collaborations. The position is site-based in Slough, with optional remote...Read More>>.

Posted: September 30th, 2026
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Principal Data Scientist I

Company IconElsevier
Location IconLondon

Overview As Principal Data Scientist, you provide technical leadership across data science teams to design AI, NLP, and generative AI solutions for knowledge discovery and decision support. You set standards, quality, and governance while g...Read More>>.

Posted: September 30th, 2026
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Principal Data Scientist

Company IconFaculty
Location IconLondon

Overview Enthusiastic Principal Data Scientist who leads highly technical, high-impact AI projects for top clients in regulated sectors. You set technical direction for the data science team, mentor colleagues, and elevate the practice thro...Read More>>.

Posted: September 30th, 2026
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Principal Data Scientist

Company IconVortexa
Location IconLondon

Overview As Principal Data Scientist at Vortexa, you lead high-impact data science work on frontier energy problems, shaping production-grade AI/ML solutions. You collaborate with analysts, engineers, traders, and regulators to ensure relia...Read More>>.

Posted: September 30th, 2026
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Principal Scientist, Functional Genomics

Company IconNovo Nordisk Pharma
Location Icon

Overview In this role you will lead and shape cutting-edge functional genomics efforts to identify and validate therapeutic targets. You will drive automation-friendly screening approaches and digital data strategies to scale experimentatio...Read More>>.

Posted: September 30th, 2026
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Principal Safety Scientist - SERM

Company IconGSK
Location Icon

Overview In this role you will provide medical and scientific input for safety evaluation and risk management across clinical development and post-marketing. You will lead signal detection, produce safety assessments, and contribute to risk...Read More>>.

Posted: September 30th, 2026
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Principal Scientist, Biomarker Assay Development Bench Scientist

Company IconNovartis
Location IconCambridge

Overview As a Principal Scientist, you will lead bench research to design, develop, and qualify biomarker assays for preclinical and clinical programs across DAx. You will develop and implement ligand-binding assays (ELISA, MSD, immunoassay...Read More>>.

Posted: October 1st, 2026
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Principal Scientist PK/PD

Company IconUCB Group
Location IconBerkshire

Overview In this role you will lead the non-clinical PKPD strategy within the QCP function to enable quantitative translation from preclinical data to patient outcomes. You will work with cross-functional teams to shape drug candidates from...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Bioanalytical & Molecular Assays

Company IconModerna Therapeutics
Location Icon

Overview Join Moderna at the Harwell site to lead development of advanced molecular assays that support clinical endpoints across multiple programs. You will work across molecular biology, bioanalysis, genomics, informatics, and clinical de...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Pharmaceutical Development

Company IconIQVIA
Location IconCambridge

Overview In this Principal Scientist role, you will lead developability-focused science within a modern IQVIA Pharmaceutical Development function, combining physicochemical sciences, biopharmaceutics and AI-enabled approaches to anticipate...Read More>>.

Posted: October 1st, 2026
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Principal Research Scientist - AI Safety

Company IconFaculty
Location IconLondon

Overview In this role, you will lead Faculty’s AI safety research program, focusing on large language models and safety-critical systems. You’ll guide a small, high-agency team, drive external publications, and align research with the c...Read More>>.

Posted: October 1st, 2026
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Principal Data Scientist and ML Researcher

Company IconRobert Half
Location IconGloucestershire

Overview In this permanent role, you will partner with the Head of Data Science & Machine Learning to shape strategy and engage stakeholders. You will generate novel research ideas that give a competitive edge in the defence-focused custome...Read More>>.

Posted: October 1st, 2026
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Principal Scientist I/II, Oligonucleotide Chemistry & Innovation

Company IconNovartis
Location IconCambridge

Overview In this role you will advance Novartis’ xRNA platform by leading oligonucleotide chemistry development and cross-functional collaboration to drive RNA therapeutics from discovery through preclinical stages. You’ll mentor scient...Read More>>.

Posted: October 1st, 2026
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Principal Research Scientist

Company IconKLA-Tencor
Location IconNewport

Overview In this role you will drive the conception and hands-on development of next‑generation plasma process technologies for challenging semiconductor manufacturing problems. You will lead hardware and process solutions, advancing plas...Read More>>.

Posted: October 1st, 2026
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Principal scientist

Company IconUCB Group
Location IconBerkshire

Overview As Principal Scientist in In Vitro Pharmacology at UCB, you will drive SPR and biophysical assay data generation to support drug discovery programs. You’ll provide scientific leadership, influence project decisions, and help adva...Read More>>.

Posted: October 1st, 2026
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Principal Scientist MSAT

Company IconSRG Talent
Location IconDarlington

Overview In this MSAT-focused role, you lead complex biologics programs, guiding transfer and scale-up of bioprocesses into GMP manufacturing. You will partner with operations, quality and engineering to ensure robust, scalable processes th...Read More>>.

Posted: October 1st, 2026
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Principal Staff Scientist

Company IconWellcome Sanger Institute
Location IconHinxton

Overview In this role you lead AI/ML strategy for the Human Genetics Programme, shaping analytical methods across large-scale multiomic and clinical data. You will work with statisticians, computational scientists, and analysts to develop p...Read More>>.

Posted: October 1st, 2026
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Principal Innovation Scientist

Company IconHaleon
Location IconWeybridge

Overview In this role you will drive wellness innovation across the operating unit to support Europe’s growth goals. You will partner with commercial, R&D, regulatory and medical teams to maintain a consumer-relevant pipeline aligned with...Read More>>.

Posted: October 1st, 2026
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Principal Applied Data Scientist

Company IconLondon Stock Exchange Group
Location IconLondon

Overview In this Principal Data Scientist role, you design, build, and deploy scalable AI solutions that move beyond prototypes into production use within LSEG Workspace for financial professionals. You combine NLP/LLM expertise with strong...Read More>>.

Posted: October 1st, 2026
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Principal Scientist

Company IconIpsen
Location Icon

Overview As Principal Scientist, you will lead Cell Line Development and Upstream Process Development for biologics, guiding projects from early stage to commercial manufacture. You will provide scientific leadership across CLD and USP, men...Read More>>.

Posted: October 1st, 2026
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Life Sciences Senior Principal Scientist

Company IconPepsico
Location IconLeicester

Overview In this role you will shape and govern the EMEA Life Sciences research portfolio, translating global science strategies into regionally relevant programs that drive growth, claims, and reputation. You will lead scientific platforms...Read More>>.

Posted: October 1st, 2026
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Principal Research Scientist - Frontier Industrial AI

Company IconAveva Group
Location IconLondon

Overview In this role you drive frontier industrial AI research at AVEVA, turning ambitious ideas into working systems. You will lead high-impact initiatives, develop new models and architectures, and build validated prototypes that advance...Read More>>.

Posted: October 1st, 2026
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Principal Clinical Scientist

Company IconCSL
Location IconMaidenhead

Overview As Principal Clinical Scientist, you will lead clinical studies end-to-end from protocol development to final study report, guiding scientific and operational aspects in partnership with CROs. You’ll act as the anchor between the...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Operational Excellence

Company IconNovo Nordisk Pharma
Location Icon

Overview In this role you drive the continuous improvement of science delivery within TIM, optimising workflows and strengthening quality systems to enable efficient, scalable execution. You partner with cross-functional teams to accelerate...Read More>>.

Posted: October 1st, 2026
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Principal Scientist I/II, Study Quality and Compliance - Nonclinical Safety/Toxicology

Company IconNovartis
Location IconCambridge

Overview In this role you will provide scientific and operational support to the Study Quality and Compliance group within Toxicology (Preclinical Safety). You will ensure training records, CVs and job descriptions are maintained, and that...Read More>>.

Posted: October 1st, 2026
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Principal Data Scientist - AI

Company IconAnaplan
Location IconLondon

Overview As Principal Data Scientist at Anaplan, you will architect and deploy AI solutions across the full stack of Anaplan AI applications, from model integration to intuitive user interfaces. You will lead advanced modeling and GenAI ini...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Inflammation Research

Company IconGILEAD Sciences
Location Icon

Overview In this role, you lead a team of scientists focused on developing novel biologic therapies for autoimmune disease. You’ll oversee in vitro and in vivo pharmacology studies to support lead and early discovery programs, delivering...Read More>>.

Posted: October 1st, 2026
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Principal Machine Learning Scientist

Company IconTripAdvisor
Location IconLondon

Overview As Principal Machine Learning Scientist, you anchor the Trips discovery engine, shaping ML strategy and production systems that power search, discovery, and itineraries for millions of users. You bridge cutting-edge AI research wit...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist / Director – Computational Chemistry (IDD)

Company IconPharmaron Biologics
Location IconHoddesdon

Overview In this senior role you lead the Computational Sciences strategy within Pharmaron's Integrated Drug Discovery (IDD) programs, shaping design and optimization of multi-modality ligands. You guide cross-functional teams, drive AI-ena...Read More>>.

Posted: October 1st, 2026
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Principal Data Scientist - Finance & Transformation

Company IconBritish Airways
Location IconHeathrow

Overview As Principal Data Scientist you will lead end-to-end data science delivery within the Data & AI function, shaping high-value models and decision-support tools. You’ll work in Agile squads to design, productionise and maintain sca...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist, Translational Profiling Imaging

Company IconNovartis
Location IconCambridge

Overview In this role you lead a translational profiling group focused on advanced imaging and spatial biology to enable target discovery and validation across disease areas. You shape imaging capabilities and integrate multi-omics and mole...Read More>>.

Posted: October 1st, 2026
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Principal Scientist II, Translational Biomarker Strategy Lead

Company IconNovartis
Location IconCambridge

Overview In this role you will lead and shape preclinical and translational biomarker strategies for DAx programs, guiding target validation to early clinical planning. You will act as the biomarker representative on project teams, coordina...Read More>>.

Posted: October 1st, 2026
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Sr Principal Scientist / Associate Director, Biomarker Assay Development Laboratory

Company IconNovartis
Location IconCambridge

Overview In this role you lead a biomarker assay development lab to enable translational decisions across discovery to clinical development. You will guide a high-performing team and collaborate with translational medicine, data science, an...Read More>>.

Posted: October 1st, 2026
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Principal Scientist II - Pharmacology

Company IconNovartis
Location IconCambridge

Overview In this role you lead the design and execution of in vivo anti-tumor efficacy and PK/PD studies to evaluate cancer drug candidates in CDX, PDX, and syngeneic models. You work within the Oncology Pharmacology team in Cambridge to de...Read More>>.

Posted: October 1st, 2026
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Principal Product Data Scientist

Company IconTripAdvisor
Location IconLondon

Overview As a Principal Product Data Scientist, you lead the data science vision for Product, shaping tooling, platforms, and AI-driven capabilities that power better customer experiences. You’ll influence senior leaders and cross-functio...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist / Assoc Director, Oncology Translational Research

Company IconNovartis
Location IconCambridge

Overview In this role you will lead the development and deployment of scalable digital pathology workflows and AI-enabled image analysis for oncology biomarkers. You’ll work with cross-site teams to advance HALO AI workflows and RareCyte...Read More>>.

Posted: October 1st, 2026
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Principal Scientist - Protein Mass Spectrometry

Company IconGSK
Location Icon

Overview In this role you apply protein mass spectrometry expertise to characterise biotherapeutics, guiding early-phase development and critical decisions on quality attributes. You’ll work across Discovery and CMC Development in a matri...Read More>>.

Posted: October 1st, 2026
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Principal Data Scientist - Water Sector

Company IconStantec
Location IconHigh Wycombe

Overview As a Principal Data Scientist at Stantec, you will lead advanced analytics initiatives to drive digital transformation in the water sector. You will work with Analysts and Data Engineers to shape data-driven strategies for asset op...Read More>>.

Posted: October 1st, 2026
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Senior Principal Scientist, Clinical Biomarkers

Company IconIpsen
Location IconLondon

Overview As Clinical Biomarker Lead, you will define and drive biomarker strategies to enable data-driven decisions across Ipsen’s oncology and rare disease programs. You will partner with cross-functional teams to ensure scientifically r...Read More>>.

Posted: October 1st, 2026
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Principal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting)

Company IconNovartis
Location IconCambridge

Overview In this role you apply AI-driven strategies to advance clinical pharmacology support for transformative medicines. You will shape AI-enabled solutions across PKS/clinical pharmacology, accelerating deliverables and enabling data-dr...Read More>>.

Posted: October 1st, 2026
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Principal Scientist, Immunogenicity and Ligand Binding Assays

Company IconModerna Therapeutics
Location Icon

Overview In this role you will lead and hands-on oversee LBA-based bioanalysis for Moderna’s mRNA-LNP programs, enabling critical clinical decisions with rigorous science and regulatory compliance. You will drive immunogenicity and ADA/ne...Read More>>.

Posted: October 1st, 2026
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Principal Data Scientist & Machine Learning Researcher

Company IconRaytheon
Location IconLondon

Overview In this role, you will help shape AI/ML strategy within the Strategic Research Group and lead multiple projects end-to-end. You contribute to technical direction, engage with customers and stakeholders, and deliver robust AI/ML sol...Read More>>.

Posted: October 1st, 2026
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Principal Scientist

Company IconHyper Recruitment Solutions
Location IconEdinburgh

Overview In this Principal Scientist role, you will lead structural biology client projects, shaping project strategy and scientific output. You will apply X-ray Crystallography and Cryo-EM to support discovery programs while mentoring coll...Read More>>.

Posted: October 1st, 2026
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Principal Scientist – High-Throughput Bioprocess Technology Development 

Company IconLonza
Location IconSlough

Overview In this role you will drive automation across biopharma R&D and development, implementing and tuning automated workflows for key assays. You will work with cross-functional teams to integrate liquid handling systems, ELN, LIMS, and...Read More>>.

Posted: October 2nd, 2026
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Computational Biologics Design – Associate Principal Scientist

Company IconAstraZeneca
Location IconCambridge

Overview In this role you will lead in silico design for biologics across oncology, respiratory and cardiovascular areas, translating structural and experimental data into actionable design insights. You will work closely with discovery and...Read More>>.

Posted: October 3rd, 2026
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